Resins PFG-4, PFG-8 and a reference resin (resin A) were used as binders of MgO-C bricks, effects of the resins with different molecular structures on wettability of magnesia, on physical properties, mechanical properties, oxidation resistance and thermal expansion properties of MgO-C bricks were researched. The results show that the microstructures of solidified resins with different molecular structures are different, which have obvious effect on the cold mechanical properties of MgO-C brick, but little effect on the oxidation resistance, thermal performance and expansion properties.